Painkillers?

When you take a painkiller how does it "know" which part of the body is in pain?
Answer:
actually, there are chemical triggers which detects the inflammed area.

for example, our tissues ave plasma and synovial fluids;

the synoval fluids is the affected area for pain, the plasma is not.

Now, the drugs identifies/detects the pain triggers bec. of chemical compositions in the synovial fluids and therefore the active ingredient in the drug attaches to the synovial fluid and does it work to alleviate the pain

and that is how you are relieved of the pain.

I am not kidding - go to a drug site example lumiracoxib and search for the mechanism of action. what i said here is true.

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magic

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Good question, always wondered this myself..love to see how.....unfortunately I have no idea!!

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it goes through whole body

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it doesnt matter as long *** the pain goes away

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I think it just works on your whole body you just don't feel it in other places than the one hurtin.

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I have always wondered this too. Something to do with synapses methinks.............

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it works on the pain bit of your brain telling it to switch off sort of if that made sense

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it targets the part of the brain
that makes you feel pain.
not the whole body as some have said.
you know you are in pain cos your brain says so
so it reacts to that part of the brain.

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I dont think it knows,it just helps the pain where ever it is in the body,i guess some pills work better on some parts than others.

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it effects a chemical that connects the cells and stops it from feeling pain.. thats not exactly accurate but we were taught it at gcse so its a while back for me.

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Along the path of sensory nerves in the body, you come across a 'bridge', I cannot remember the proper name, basically they are a break in the nerve, and enzymes carry the signal across this 'break', the signal is a substrate, and stimulates the realize of a particular enzyme, so you have one for pain, taste, etc. A pain killer, or anesthetic, inhibits the effect of the enzyme, thus the pain is stopped to your knowledge, and not your other senses, so you think the pain killer knows where the pain is.

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it dosent it gets in the blood strem and nums the lot.

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i think a message is sent to your brain once the painkiller is in your system and it knows which part of the body needs the medicine

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ibuprofen works by reducing the amount of prostaglandins synthesis thus reducing inflammation which then reduces pain.
paracetemol works a similar way but also inhibits the cyclooxygenase enzyme as does asprin. thus reducing an inflammatory response.

morphine is an opioid drug which works by blocking the nerves thus reducing pain.

pain killing drugs tend to work on either all areas of the body or where there is inflammation so you have pain relief

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Painkillers don't know what hurts, but YOU do.

All pain is felt in your brain. If you reduce inflammation with a non-steroidal painkiller, or block opiate receptors with a narcotic, that happens everywhere.

You interpret the effects of the drug as "my headache is gone" or "my knee hurts less".

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it doesnt "know" it intercepts ALL the nerves in the body and eases pain all over your body- however, as you feel pain in a particular part when the pain has gone you notice it.

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