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Saturday, October 31, 2009

Norepinephrine related medical question?

1) Is Norepinephrine available in oral form?

2) If not, if Norepinephrine is mixed with dextrose, can it digested?

3) If exposed to air, does color turns PINK signalling oxidation?

4) How much of drug efficiency is lost due to oxidation?
Answer:
Norepinephrine, (Levarterenol) in normal state, is a whitish semiyellow powder, soluble in water, available to the public ONLY in vials, not available in oral form (pills) , (only ampules with 1 mililiter of the injectable fluid), Norepinephrine when ingestedn and exposed to stomach acids, is rapidly transformed into mandelic acid and benzoic acid, which have no effects on pressure, nor the sympathetic system because of fast destruction, ...
You dont need to expose norepinephrine to air , in order for it to obtain a copper- brownish - like color....it means that a good part of the compound has been dissociated ito two components that are inactive, and is old , and useless. even in the closed vial,,,(exposed to the light for some time).....dont use it...it wont harm you, however, no medical or therapeutioc result will be obtained from that...BETTER DISCARD IT...ITS SAFER.
The answer of the amount of substance rendered useless by oxydation ,is more that 60%....better get another batch.......
1) no
2) no
3) maybe or contaminated
4) no evidence to prove this

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