Oxygen use in the human body?

1: Does anybody know how much O2, (I'm talking the element not the atmosphere), the human body uses during rest or periods of inactivity?? (preferably in Liters per Minute (lpm)
2: Does that change in the case of a person mostly bed-ridden with lung problems?? (ie. COPD or "fibrosis") I realize the efficiency of the gas exchange would be abnormal (I'm guessing lower).
2a: If the lpm does not change, (referring back to question 2), does the volume of the air required change?? (in this case 'air' is the total gas mixture inhaled)
3: How much total volume of normal air does a person breath per minute. (again, preferably in lpm)
3a: Does that change for someone in the above mentioned state??
4: Can someone get too much oxygen??
4a: If 4 is true, what does it do to the body and what are the signs and symptoms??
(I've heard talk about "burning up someone's brain" by having "too much oxygen".)

thank you for your time and effort;
bdraft
Answer:
Most people require 200-300 ml/min of oxygen. That's why our anesthesia machines won't go below that amount. (0.2-0.3 lpm)
When we breathe in air at 21%, we don't use all that oxygen - we breathe out about 17% oxygen.

Bedridden people require less, but would have to have higher FiO2 to compensate for poor gas exchange.

Volume is not so much the issue as concentration.

Normal minute ventilation is 5-7 liters/min. Yes, it can change depending on the lung problem.

COPD patients may lose their hypercarbic drive to breathe and depend on a hypoxic drive. They CAN get too much O2, and stop breathing.

No brain burning. Just decreased resp rate, increased Co2, maybe hypoxemia, decreased level of consciousness (from increased CO2)

Hope that helps.

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Average 4 seconds per breathing in and out normaly, the vital capacity 脳21%脳24hours脳3600梅4= the Oxygen used a day.

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