Pathophysiology,signs and symptoms,nursing intervention of nodular adenomatous goiter??

Answer:
Pathophysiology

The histopathology varies with etiology and age of the goiter. Initially, uniform follicular epithelial hyperplasia (diffuse goiter) is present with an increase in thyroid mass. As the disorder persists, the thyroid architecture loses uniformity, with the development of areas of involution and fibrosis interspersed with areas of focal hyperplasia. This process results in multiple nodules (multinodular goiter). On nuclear scintigraphy, some nodules are hot, with high isotope uptake (autonomous) or cold, with low isotope uptake, compared with the normal thyroid tissue. The development of nodules correlates with the development of functional autonomy and reduction in thyroid-stimulating hormone (TSH) levels. Clinically, the natural history of a nontoxic goiter is growth, nodule production, and functional autonomy resulting in thyrotoxicosis in a minority of patients.

Signs / symptoms

dyspnea
stridor
Hemorrhage
bronchitis
dysphagia.
hoarseness.
facial plethora
and dilated neck veins

Nursing intervention

Diets low in iodine need supplementation, especially in developing countries where government-supported iodine supplementation is not available.

Patients taking iodine supplements may need a reduction to avoid iodine-induced thyroid disease in predisposed individuals.

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try this link:

http://ocw.tufts.edu/content/14/lecturen...

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